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Human LRRC3B Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB7635V Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB7635V-100UG

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Human LRRC3B Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human LRRC3B in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG1 Clone # 758315
Purification
Protein A or G purified
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human LRRC3B
Phe28-Ala205
Accession # Q96PB8
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: LRRC3B

LRRC3B, also known as LRP15, is a transmembrane leucine-rich protein that is downregulated by promoter methylation in gastric and colorectal cancers. It confers resistance to ultraviolet light-induced DNA damage and functions as a tumor suppressor. Mature human LRRC3B contains an LRR N-terminal domain (aa 34-64), 3 LRR repeats (aa 65-135), an LRR C-terminal domain (aa 145-197), a transmembrane segment (aa 205-225), and a C-terminal region (aa 226-259). Within aa 28-205, human LRRC3B shares 100% aa sequence identity with mouse and rat LRRC3B.

Long Name
Leucine Rich Repeat Containing 3B
Entrez Gene IDs
116135 (Human); 218763 (Mouse)
Alternate Names
leucine rich repeat containing 3B; leucine-rich repeat-containing protein 3B; LRP15; LRP15Leucine-rich repeat protein LRP15; LRRC3B; MGC102927

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