Human Lymphotoxin beta /TNFSF3 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB1684S Datasheet / COA / SDS

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FAB1684S-100UG

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Human Lymphotoxin beta /TNFSF3 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Lymphotoxin alpha beta heterotrimers in direct ELISAs and Western blots. This antibody detects an epitope in the Lymphotoxin beta subunit. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) Lymphotoxin alpha, rh

Source

Monoclonal Mouse IgG2b Clone # 135105

Purification

Protein A or G purified

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Lymphotoxin Î±/Î²

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Lymphotoxin beta/TNFSF3

Lymphotoxin beta is a type II transmembrane protein member of the TNF ligand superfamily and is now designated TNFSF3. Lymphotoxin beta associates with Lymphotoxin alpha to form two types of heterotrimers, Lymphotoxin alpha ₁ beta ₂ and Lymphotoxin alpha ₂ beta ₁. Lymphotoxin beta is expressed by activated CD4 T cells, unpolarized IL‑2‑secreting effector T cells, and Th1 effector cells.

Long Name

Lymphotoxin beta

Entrez Gene IDs

4050 (Human); 102135554 (Cynomolgus Monkey)

Alternate Names

LTB; lymphotoxin beta (TNF superfamily, member 3); Lymphotoxin beta; lymphotoxin-beta; p33; TNFCTNF-C; TNFSF3; TNFSF3LT-beta; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3