Human Lymphotoxin  beta /TNFSF3 Antibody

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Product Details
Citations (2)
Supplemental Products

Human Lymphotoxin  beta /TNFSF3 Antibody Summary

Species Reactivity
Detects human Lymphotoxin alpha beta heterotrimers in direct ELISAs and Western blots. This antibody detects an epitope in the Lymphotoxin  beta subunit. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) Lymphotoxin  alpha, rhAPRIL, rhBAFF, rhTNF‑ alpha, rhTWEAK, rhEDA‑A2, rhEDA, rhTRAIL, rhVEGI, rhTRANCE, rhFas Ligand, or rhOX40 Ligand.
Monoclonal Mouse IgG2B Clone # 135105
Protein A or G purified from hybridoma culture supernatant
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Lymphotoxin  alpha / beta
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
Human Lymphotoxin  beta /TNFSF3

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Lymphotoxin beta/TNFSF3

Lymphotoxin beta is a type II transmembrane protein member of the TNF ligand superfamily and is now designated TNFSF3. Lymphotoxin beta associates with Lymphotoxin alpha to form two types of heterotrimers, Lymphotoxin alpha 1 beta 2 and Lymphotoxin  alpha 2 beta 1. Lymphotoxin beta is expressed by activated CD4 T cells, unpolarized IL‑2‑secreting effector T cells, and Th1 effector cells.

Long Name
Lymphotoxin beta
Entrez Gene IDs
4050 (Human); 102135554 (Cynomolgus Monkey)
Alternate Names
LTB; lymphotoxin beta (TNF superfamily, member 3); Lymphotoxin beta; lymphotoxin-beta; p33; TNFCTNF-C; TNFSF3; TNFSF3LT-beta; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3

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Citations for Human Lymphotoxin  beta /TNFSF3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Microarray analysis of gene expression by microdissected epidermis and dermis in mycosis fungoides and adult T-cell leukemia/lymphoma.
    Authors: Hashikawa K, Yasumoto S, Nakashima K, Arakawa F, Kiyasu J, Kimura Y, Saruta H, Nakama T, Yasuda K, Tashiro K, Kuhara S, Hashimoto T, Ohshima K
    Int J Oncol, 2014;45(3):1200-8.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  2. Lymphotoxin-alphabeta heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis.
    Authors: Young J, Yu X, Wolslegel K
    Cytokine, 2010;51(1):78-86.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot


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