Human MAG/Siglec-4a (NP_002352) VersaClone cDNA Summary
MAG (Myelin-Associated Glycoprotein), also known as Siglec-4a, is a transmembrane lectin that preferentially binds to alpha-2,3-linked sialic acid terminal carbohydrates on cell surface molecules. It is expressed by myelinating oligodendrocytes and Schwann cells and plays an important role in axon-myelin stability. MAG also regulates axon structure at nodes of Ranvier, inhibits neurite outgrowth, and protects neurons from excitotoxicity. It interacts with the gangliosides GD1a and GT1b, the Nogo receptors NgR1 and NgR2/NgRH1, Integrin beta 1/CD29, and PIR-B. Proteolytic cleavage releases a soluble form that is released from myelin in large quantities.
No product specific FAQs exist for this product, however you mayView all cDNA Clone FAQs
Reviews for Human MAG/Siglec-4a (NP_002352) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human MAG/Siglec-4a (NP_002352) VersaClone cDNA and earn rewards!
Have you used Human MAG/Siglec-4a (NP_002352) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image