Human MCT1/SLC16A1 APC-conjugated Antibody

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Detection of MCT1/SLC16A1 in HEK293 Human Cell Line Transfected with Human MCT1/SLC16A1 and eGFP by Flow Cytometry.
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Human MCT1/SLC16A1 APC-conjugated Antibody Summary

Species Reactivity
Stains human MCT1/SLC16A1 transfected cells but not irrelevant transfectants.
Monoclonal Mouse IgG2A Clone # 882616
Protein A or G purified from hybridoma culture supernatant
NS0 mouse myeloma cell line transfected with human MCT1/SLC16A1
Accession # P53985
Supplied in a saline solution containing BSA and Sodium Azide.
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)


Recommended Concentration
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of MCT1/SLC16A1 antibody in HEK293 Human Cell Line Transfected with Human MCT1/SLC16A1 and eGFP antibody by Flow Cytometry. View Larger

Detection of MCT1/SLC16A1 in HEK293 Human Cell Line Transfected with Human MCT1/SLC16A1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human MCT1/SLC16A1 or (B) irrelevant transfectant and eGFP was stained with Mouse Anti-Human MCT1/SLC16A1 APC-conjugated Monoclonal Antibody (Catalog # FAB8275A). Quadrant markers were set based on control antibody staining (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: MCT1/SLC16A1

Solute Carrier, family 16, member 1 (SLC16A1) encodes Monocarboxylic Acid Transporter 1 (MCT1).  MCT1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. MCT1 has been found to be important in lactate uptake in cancer cells, and blockade of MCT1 may inhibit lactate-induced HIF-1 activation (1).

  1. Sonveaux, P. et al (2012) PLoS ONE 7:e33418.
Long Name
Monocarboxylic Acid Transporter 1 (Solute Carrier Family 16 Member 1)
Entrez Gene IDs
6566 (Human); 20501 (Mouse); 25027 (Rat)
Alternate Names
FLJ36745; HHF7; MCT 1; MCT; MCT1; MCT1MGC44475; member 1; monocarboxylate transporter 1; SLC16A1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)

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