Human MCT1/SLC16A1 PE-conjugated Antibody FAB8275P: R&D Systems

Human MCT1/SLC16A1 PE-conjugated Antibody

  • Species Reactivity
  • Specificity
    Stains human MCT1/SLC16A1 transfected cells but not irrelevant transfectants.
  • Source
    Monoclonal Mouse IgG2A Clone # 882616
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    NS0 mouse myeloma cell line transfected with human MCT1/SLC16A1
    Accession # P53985
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of MCT1/SLC16A1 in HEK293 Human Cell Line Transfected with Human MCT1/SLC16A1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human MCT1/SLC16A1 or (B) irrevelant transfectant and eGFP was stained with Mouse Anti-Human MCT1/SLC16A1 PE‑conjugated Monoclonal Antibody (Catalog # FAB8275P). Quadrant markers were set based on control antibody staining (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: MCT1/SLC16A1

Solute Carrier, family 16, member 1 (SLC16A1) encodes Monocarboxylic Acid Transporter 1 (MCT1).  MCT1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. MCT1 has been found to be important in lactate uptake in cancer cells, and blockade of MCT1 may inhibit lactate-induced HIF-1 activation (1).

  • References:
    1. Sonveaux, P. et al (2012) PLoS ONE 7:e33418.
  • Long Name:
    Monocarboxylic Acid Transporter 1 (Solute Carrier Family 16 Member 1)
  • Entrez Gene IDs:
    6566 (Human); 20501 (Mouse); 25027 (Rat)
  • Alternate Names:
    HHF7; malignant T cell amplified sequence 1; Malignant T-Cell-Amplified Sequence 1; MCT1; MCT-1; Multiple Copies T-Cell Malignancies; SLC16A1
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Mouse IgG2A PE-conjugated Antibody

Ctrl IC003P 13  
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Staining Reagents
Description Application Cat# Citations Images  

Flow Cytometry Staining Buffer (1X)

Flow FC001 6
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 4
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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