Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Mouse IgG2A Clone # 882616
View all MCT1/SLC16A1 Primary Antibodies »

Product Specifications

Immunogen

NS0 mouse myeloma cell line transfected with human MCT1/SLC16A1
Met1-Val500
Accession # P53985

Specificity

Stains human MCT1/SLC16A1 transfected cells but not irrelevant transfectants.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human MCT1/SLC16A1 PE‑conjugated Antibody

Detection of MCT1/SLC16A1 antibody in HEK293 Human Cell Line Transfected with Human MCT1/SLC16A1 and eGFP antibody by Flow Cytometry.

Detection of MCT1/SLC16A1 in HEK293 Human Cell Line Transfected with Human MCT1/SLC16A1 and eGFP by Flow Cytometry.

Mouse Anti-Human MCT1/SLC16A1 PE-conjugated Monoclonal Antibody (Catalog # FAB8275P) was detected in (A) HEK293 human embryonic kidney cell line transfected with human MCT1/SLC16A1 and eGFP or (B) Irrelevant transfectants. Quadrant markers were set based on control antibody staining (IC003P). View our protocol for Staining Membrane-associated Proteins.

Applications for Human MCT1/SLC16A1 PE‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with human MCT1/SLC16A1 and eGFP

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
Spectra Viewer

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: MCT1/SLC16A1

Solute Carrier, family 16, member 1 (SLC16A1) encodes Monocarboxylic Acid Transporter 1 (MCT1).  MCT1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. MCT1 has been found to be important in lactate uptake in cancer cells, and blockade of MCT1 may inhibit lactate-induced HIF-1 activation (1).

References

  1. Sonveaux, P. et al (2012) PLoS ONE 7:e33418.

Long Name

Monocarboxylic Acid Transporter 1 (Solute Carrier Family 16 Member 1)

Alternate Names

HHF7, SLC16A1

Entrez Gene IDs

6566 (Human); 20501 (Mouse); 25027 (Rat)

Gene Symbol

SLC16A1

UniProt

P53985

Additional MCT1/SLC16A1 Products

Product Documents for Human MCT1/SLC16A1 PE‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human MCT1/SLC16A1 PE‑conjugated Antibody

For research use only

Related Research Areas

Glucose Homeostasis

Citations for Human MCT1/SLC16A1 PE‑conjugated Antibody

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