MICL is a member of the group V subfamily of the C-type lectin-like family of molecules. It is found on the cell surface, contains an ITIM (immunoreceptor tyrosine-based inhibitory motif) in its cytoplasmic domain, and is N-glycosylated. Expression of MICL is restricted to granulocytes and monocytes, and it may function as a negative regulator of these cell types. At least three isoforms of MICL are generated by alternative splicing, including one that lacks the transmembrane domain.
Human MICL/CLEC12A (NP_612210) VersaClone cDNA
R&D Systems | Catalog # RDC1485
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: MICL/CLEC12A
Long Name
Myeloid Inhibitory C-type Lectin-like Receptor
Alternate Names
CD371, CLEC12A, CLL-1, DCAL-2
Gene Symbol
CLEC12A
UniProt
Additional MICL/CLEC12A Products
Product Documents for Human MICL/CLEC12A (NP_612210) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human MICL/CLEC12A (NP_612210) VersaClone cDNA
For research use only
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Associated Pathways
