Home / ATM / Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor® 700-conjugated Antibody

Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor® 700-conjugated Antibody

Catalog #: AF1655N Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF1655N-100UG

Save 15% on Select RUO Reagents. See Details. 

Product Details
FAQs
Supplemental Products
Reviews
Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human ATM when phosphorylated at S1981. Also detects the comparable phosphorylated sites in mouse ATM (S1987) and rat ATM (S1952).
Source
Polyclonal Rabbit IgG
Purification
Antigen Affinity-purified
Immunogen
Phosphopeptide containing human ATM S1981 site
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ATM

The Ataxia telangiectasia-mutated (ATM) protein kinase exists as a dimer in the cell nucleus. Changes in DNA structure induced by genotoxic stress lead to activation of ATM and phosphorylation of S1981 in trans. Once S1981 is phosphorylated, the dimer dissociates and active ATM monomers signal to downstream targets.

Long Name
Ataxia Telangiectasia-mutated
Entrez Gene IDs
472 (Human); 11920 (Mouse)
Alternate Names
AT mutated; A-T mutated; AT1; ATA; ataxia telangiectasia mutated (includes complementation groups A, C and D); ataxia telangiectasia mutated; ATC; ATD; ATDC; ATE; ATM serine/threonine kinase; ATM; DKFZp781A0353; EC 2.7.11.1; MGC74674; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1; TPLL

Product Datasheets

You must select a language.

x
Product Datasheet
COA

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor® 700-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor® 700-conjugated Antibody and earn rewards!

Have you used Human/Mouse/Rat Phospho-ATM (S1981) Alexa Fluor® 700-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review