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Human/Mouse/Rat XPD Alexa Fluor® 647-conjugated Antibody

Catalog #: AF3296R Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF3296R-100UG

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Human/Mouse/Rat XPD Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human, mouse, and rat XPD in Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human XPD
Met1-Gly360
Accession # P18074
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: XPD

The Xeroderma Pigmentosum D (XPD) protein is a DNA helicase that acts as a subunit of the RNA polymerase II complex during nucleotide excision repair (NER) and transcription-coupled repair (TCR). XPD is also involved in p53-mediated apoptosis. XP patients exhibit hypersensitivity to ultraviolet light and have a heightened incidence of skin cancer.

Long Name
Xeroderma Pigmentosum D
Entrez Gene IDs
2068 (Human); 13871 (Mouse); 308415 (Rat)
Alternate Names
Basic transcription factor 2 80 kDa subunit; BTF2 p80; COFS2; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; EC 3.6.1; EC 3.6.4.12; EM9; EM9TFIIH basal transcription factor complex 80 kDa subunit; ERCC2; excision repair cross-complementing rodent repair deficiency, complementationgroup 2; MAG; MGC102762; MGC126218; MGC126219; TFIIH 80 kDa subunit; TFIIH basal transcription factor complex helicase subunit; TFIIH basal transcription factor complex helicase XPD subunit; TTD; xeroderma pigmentosum complementary group D; Xeroderma pigmentosum group D-complementing protein; XPD; XPDC; XPDTFIIH p80

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