Human NAALADase-like 2/NAALADL2 Alexa Fluor® 488-conjugated Antibody

FAB4665G has been discontinued. View all NAALADase-like 2/NAALADL2 products.
Datasheet / CoA / SDS
Product Details
  • Species Reactivity
  • Specificity
    Detects human NAALADase‑like 2/NAALADL2 in direct ELISAs.
  • Source
    Monoclonal Mouse IgG1 Clone # 817225
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Mouse myeloma cell line NS0-derived recombinant human NAALADase‑like 2/NAALADL2
    Accession # Q58DX5
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Alexa Fluor 488
Product Datasheets

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  • Flow Cytometry
    5 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example
Detection of NAALADase‑like 2/NAALADL2 in LNCaP Human Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Mouse Anti-Human NAALADase‑like 2/NAALADL2 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB4665G, filled histogram) or isotype control antibody (Catalog # IC002G, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: NAALADase-like 2/NAALADL2

NAALADL2 (N-acetylated alpha -linked acidic dipeptidase like 2) is a member of the peptidase M28 family of enzymes. It is presumably a type II transmembrane (TM) protein that may have O-glycosyl hydrolase activity. Human NAALADL2 is 795 amino acids (aa) in length. It is believed to contain a cytoplasmic and TM segment at the N-terminus, followed by a peptidase domain (aa 444‑596) and a TfR-like dimerization region (aa 688‑777). There are multiple splice forms. One shows a 4 aa substitution for aa 292‑795, a second shows an alternate start site at Met18 with a 24 aa substitution for aa 314‑795, and a third contains an alternate start site at Met283, accompanied by a deletion of aa 363‑411 and 633‑795. Over aa 152‑795, human NAADADL2 shares 87% and 82% aa sequence identity with mouse and canine NAADADL2, respectively.

  • Long Name:
    N-Acetylated Alpha-Linked Acidic Dipeptidase-like 2
  • Entrez Gene IDs:
    254827 (Human); 635702 (Mouse); 499583 (Rat)
  • Alternate Names:
    inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; NAALADase L2; NAALADase like 2; NAALADase-like 2; NAALADL2; N-acetylated alpha-linked acidic dipeptidase 2; N-acetylated alpha-linked acidic dipeptidase-like 2
Related Research Areas


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