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Human Neurogenin-1 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB3524S Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB3524S-100UG

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Human Neurogenin-1 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Neurogenin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Neurogenin-3 is observed.
Source
Monoclonal Mouse IgG1 Clone # 309707
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human Neurogenin‑1
Ala145-His237
Accession # NP_006152
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Neurogenin-1

Neurogenin-1 is a 26 kDa developmentally expressed nuclear protein of the basic helix-loop-helix (bHLH) family, class B subfamily. bHLH proteins are transcription factors that form dimers to bind DNA. NGN1 is expressed only in embryonic neural tissue and supports neuronal differentiation but inhibits glial cell differentiation. Human Neurogenin-1 shows 93% amino acid identity with both mouse and rat Neurogenin-1 over the sequence used as an immunogen.

Entrez Gene IDs
4762 (Human); 18014 (Mouse)
Alternate Names
AKA; BHLHA6; bHLHa6NGN-1; Class A basic helix-loop-helix protein 6; Math4C; NEUROD3; NEUROD3neurogenic differentiation 3; NEUROG1; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; neurogenin 1; Neurogenin1; Neurogenin-1; NGN; ngn1

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