Human NTS2/NTSR2 (AAH22501) VersaClone cDNA Summary
Binding and pharmacological studies demonstrate that NTSR2 binds neurotensin as well as several other ligands already described for NTSR1. Unlike NTSR1, NTSR2 recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. NTSR2 may be of physiological importance and a natural agonist for the receptor may exist.
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