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Human OCTN2/SLC22A5 (NP_003051) VersaClone cDNA

Catalog #: RDC0507 Datasheet / COA / SDS
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RDC0507
R&D Systems VersaClone cDNA Plasmids
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Human OCTN2/SLC22A5 (NP_003051) VersaClone cDNA Summary

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

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Background: OCTN2/SLC22A5

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for the elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A5 is an integral plasma membrane protein which functions as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. Mutations in SLC22A5 are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Long Name
Solute Carrier Family 22 (Organic Cation/Carnitin Transporter) Member 5
Entrez Gene IDs
6584 (Human); 20520 (Mouse); 29726 (Rat)
Alternate Names
CDSP; FLJ46769; High-affinity sodium-dependent carnitine cotransporter; OCTN2; OCTN2high-affinity sodium dependent carnitine cotransporter; OCTN2VT; organic cation transporter 2; organic cation transporter 5; Organic cation/carnitine transporter 2; SCD; SLC22A5; solute carrier family 22 (organic cation transporter), member 5; solute carrier family 22 (organic cation/carnitine transporter), member 5; solute carrier family 22 member 5

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