Human p53R2 Alexa Fluor® 405-conjugated Antibody

Catalog #: AF3788V Datasheet / COA / SDS

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AF3788V-100UG

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All p53R2 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human p53R2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human p53R2 in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human p53R2
Met1-Lys180
Accession # Q7LG56

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: p53R2

The p53-inducible ribonucleotide reductase (p53R2) shares similarity with the R2 subunit of ribonucleotide reductase. Both function to provide dNTPs for DNA synthesis. p53R2 is induced in response to genotoxic stress, whereas the R2 functions under homeostatic conditions. When the expression of p53R2 is decreased, cells exhibit decreased ribonucleotide reductase activity, DNA repair activity, and cellular survival in response to genotoxins.

Entrez Gene IDs

50484 (Human); 382985 (Mouse)

Alternate Names

EC 1.17.4.1; MGC102856; MGC42116; MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; P53R2DKFZp686M05248; PEOA5; ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); RRM2B; TP53-inducible ribonucleotide reductase M2 B