Human PCSK9 (NP_777596) VersaClone cDNA

R&D Systems | Catalog # RDC2709

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Proprotein Convertase 9/PCSK9

PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.

Alternate Names

FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9

Entrez Gene IDs

255738 (Human); 100102 (Mouse); 298296 (Rat); 102142788 (Cynomolgus Monkey)

Gene Symbol

PCSK9

UniProt

Additional Proprotein Convertase 9/PCSK9 Products

Product Documents for Human PCSK9 (NP_777596) VersaClone cDNA

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human PCSK9 (NP_777596) VersaClone cDNA

For research use only

Related Research Areas

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