PIWIL1 (piwi-like 1), also called HIWI (human homolog of drosophila piwi), is a cytoplasmic protein of the PIWI subgroup of the Argonaute family. PIWI domains bind a class of ~29-30 nucleotide RNAs termed piRNAs (piwi domain-binding RNAs). PIWIL1 orthologs are expressed with piRNAs in germ cells and are essential for spermatogenesis in mice. CD34+ hematopoietic progenitor cell PIWIL1 is downregulated upon differentiation. When overexpressed in leukemic cell lines, PIWIL1 inhibits growth and induces apoptosis.
Human PIWIL1/HIWI (NP_004755) VersaClone cDNA
R&D Systems | Catalog # RDC2832
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PIWIL1/HIWI
Long Name
Piwi-like Protein 1
Alternate Names
HIWI, MIWI
Entrez Gene IDs
9271 (Human)
Gene Symbol
PIWIL1
UniProt
Additional PIWIL1/HIWI Products
Product Documents for Human PIWIL1/HIWI (NP_004755) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human PIWIL1/HIWI (NP_004755) VersaClone cDNA
For research use only
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