|Detection of Podocalyxin in BG01V Human Embryonic Stem Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human Podocalyxin Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB1658G, filled histogram) or isotype control antibody (Catalog # IC003G, open histogram). View our protocol for Staining Membrane-associated Proteins.|
Podocalyxin, also known as Podocalyxin-Like Protein-1 (PCLP1 or PODXL), is a type I transmembrane glycoprotein. It belongs to the CD34/Podocalyxin family of sialomucins that share structural similarity and sequence homology (1). Podocalyxin is a major sialoprotein in the podocytes of the kidney glomerulus and is also expressed by both endothelium and multipotent hematopoietic progenitors (2). It has been identified as a novel cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.
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