Home / POU2F3 / Human POU2F3 Alexa Fluor® 405-conjugated Antibody

Human POU2F3 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB11625V Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11625V-100UG
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Human POU2F3 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide specific for human POU2F3 around amino acid 100 in Direct ELISA.
Source
Monoclonal Mouse IgG2a Clone # 1091214
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # Q9UKI9
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: POU2F3

POU2F3 is a 47 kDa transcription factor involved in the regulation of the differentiation of keratinocytes. It is also a part of the POU2F3-POU2AF2/POU2AF3 complex that drives the expression of tuft-cell-specific genes. Normal and neoplastic tuft cells share a genetic requirement for POU2F3. POU2F3 is utilized as an ancillary marker for the diagnosis of neuroendocrine-low small cell lung cancer. It is also positive in mesenchymal and neuroectodermal tumors including synovial carcinoma, solitary fibrous tumor, glioblastoma, Wilms tumor and melanoma.

Long Name
POU class 2 homeobox 3
Entrez Gene IDs
25833 (Human); 18988 (Mouse); 116544 (Rat)
Alternate Names
Epoc-1; MGC126698; OCT11; OCT-11; OCT11FLJ40063; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF11; OTF-11; PLA1; PLA-1; POU class 2 homeobox 3; POU domain class 2, transcription factor 3; POU domain, class 2, transcription factor 3; POU transcription factor; POU2F3; Skn-1a; Transcription factor PLA-1; Transcription factor Skn-1

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