Human Pregnancy Zone Protein/PZP Alexa Fluor® 405-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Pregnancy Zone Protein/PZP

Pregnancy zone protein (PZP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6) is a 360 kDa secreted homodimeric glycoprotein, PZP monomer contains a region of decisive functional importance i.e. the bait region. This region serves as a substrate to a variety of proteinases, and cleavage in this domain causes a conformational change of the molecule. Human PZP is a member of the protease inhibitor I39 (alpha-2-macroglobulin) family of proteins.  Highest expression of human PZP is reported in liver, medium expression in ovary, heart and stomach. Also this protein is found in plasma.  Over aa 26-1482, human PZP is 56% aa identical to mouse PZP.

Product Datasheets

Related Research Areas

• Aspartic Proteases and Regulators
• Cysteine Proteases and Regulators
• Gametes and Fertilization
• Metalloproteases and Regulators
• Serine Proteases and Regulators