Human Proprotein Convertase 9/PCSK9 (Research Grade Alirocumab Biosimilar) Antibody

Recombinant Monoclonal Antibody For Research Use Only
Catalog # Availability Size / Price Qty
MAB10347-100
MAB10347-SP
Human Proprotein Convertase 9/PCSK9 (Research Grade Alirocumab Biosimilar) Antibody in Intracellular Staining by Flow Cytometry
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Human Proprotein Convertase 9/PCSK9 (Research Grade Alirocumab Biosimilar) Antibody Summary

Species Reactivity
Human
Specificity
Detccts Human Proprotein Convertase 9/PCSK9 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Alirocumab. This product is for research use only.
Source
Recombinant Monoclonal Human IgG1 Clone # Hu135
Purification
Protein A or G purified from cell culture supernatant
Immunogen
Human Proprotein Convertase 9/PCSK9
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Intracellular Staining by Flow Cytometry
0.25 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Intracellular Staining by Flow Cytometry Detection of Proprotein Convertase 9/PCSK9 in HeLa human carcinoma cell line by Flow Cytometry. View Larger

Detection of Proprotein Convertase 9/PCSK9 in HeLa human carcinoma cell line by Flow Cytometry. HeLa human cervical carcinoma cell line was stained with Human Anti-Human Proprotein Convertase 9/PCSK9 (Research Grade Alirocumab Biosimilar) Monoclonal Antibody (Catalog # MAB10347, filled histogram) or irrelevant antibody (open histogram) followed by APC-conjugated Anti-Human IgG Secondary Antibody (Catalog # F0135). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Proprotein Convertase 9/PCSK9

Alirocumab is a biosimilar directed against human Proprotein Convertase 9/PCSK9.

Entrez Gene IDs
255738 (Human); 100102 (Mouse); 298296 (Rat)
Alternate Names
EC 3.4.21; EC 3.4.21.111; FH3; FH3neural apoptosis regulated convertase 1; FHCL3; HCHOLA3; hypercholesterolemia, autosomal dominant 3; LDLCQ1; NARC1; NARC-1; NARC-1convertase subtilisin/kexin type 9 preproprotein; NARC1EC 3.4.21.-; Neural apoptosis-regulated convertase 1; PC9; PCSK9; Proprotein Convertase 9; proprotein convertase subtilisin/kexin type 9; Subtilisin/kexin-like protease PC9

Product Datasheets

FAQs

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Reconstitution Buffers

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