Human PSCA Antibody
Human PSCA Antibody Summary
Leu21-Ser95
Accession # O43653
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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PSCA in Human Prostate. PSCA was detected in immersion fixed paraffin-embedded sections of human prostate using Mouse Anti-Human PSCA Monoclonal Antibody (Catalog # MAB7636) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to the cell membranes of epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
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Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PSCA
PSCA (prostate stem cell antigen) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein of the Thy-1/Ly-6 family. PSCA is expressed in differentiating cells and epithelial cells of the prostate, bladder, kidney, skin, esophagus, stomach and placenta. It may be up- or down-regulated in cancer and may promote or suppress the tumor, depending on location. Mature human PSCA (amino acids 21-95) shares approximately 65% amino acid sequence identity with mouse and rat PSCA.
Product Datasheets
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