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Human PTP1B Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB1366S Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB1366S-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PTP1B Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human PTP1B in direct ELISAs.
Source
Monoclonal Mouse IgG2b Clone # 208607
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human PTP1B
Glu2-Thr435
Accession # P18031
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PTP1B

Protein tyrosine phosphatase 1B (PTP1B) dephosphorylates tyrosine residues on several proteins including c-Src, beta-catenin, and the receptors for insulin and epidermal growth factor. PTP1B knock-out mice are resistant to high-caloric intake-induced obesity and have exaggerated insulin responses, suggesting that PTP1B may play a role in regulating growth factor responsiveness.

Long Name
Protein Tyrosine Phosphatase 1B
Entrez Gene IDs
5770 (Human); 19246 (Mouse)
Alternate Names
EC 3.1.3.48; protein tyrosine phosphatase 1B; protein tyrosine phosphatase, non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP1B; PTP-1B; PTP1Bprotein tyrosine phosphatase, placental; PTPN1; tyrosine-protein phosphatase non-receptor type 1

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