Human RIPK1/RIP1 (NP_003795.2) VersaClone cDNA

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Human RIPK1/RIP1 (NP_003795.2) VersaClone cDNA
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Human RIPK1/RIP1 (NP_003795.2) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: RIPK1/RIP1

RIPK1 (Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1), also known as RIP1, contains an N-terminal protein kinase domain, a C-terminal death domain, and a unique internal region called the intermediate domain. It is a serine/threonine protein kinase and is constitutively expressed in many tissues. RIPK1 interacts with the cytoplasmic death domain of FAS and TNF receptors, and is an important element in apoptotic processes. RIPK1 has been shown to interact with a number of proteins including TRADD, TRAF1, TRAF2, and TRAF3, to form larger signaling complexes. These complexes, in turn, activate specific signaling cascades, such as NFkB.

Long Name
Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1
Entrez Gene IDs
8737 (Human); 19766 (Mouse)
Alternate Names
Cell death protein RIP; EC; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting protein; Receptor-interacting protein 1; receptor-interacting serine/threonine-protein kinase 1; RIP; Rip1 kinase; RIP1; RIP-1; RIPFLJ39204; RIPK1; Serine/threonine-protein kinase RIP


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