Human RUNX1/CBFA2 Alexa Fluor™ Plus 488‑conjugated Antibody

Name: Human RUNX1/CBFA2 Alexa Fluor™ Plus 488‑conjugated Antibody
Brand: R&D Systems
SKU: AF2399AFP488
Price: 509 USD
Availability: InStock

R&D Systems | Catalog # AF2399AFP488

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG

View all RUNX1/CBFA2 Primary Antibodies »

Product Specifications

Specificity

Detects human RUNX1 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human RUNX1/CBFA2 Alexa Fluor™ Plus 488‑conjugated Antibody

Application

Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: RUNX1/CBFA2

RUNX1, also known as CBFA2, is one of three members of the Runt-related family. The RUNX/CBFA proteins form the alpha subunits that combine with the beta subunit (CBFB) to form the heterodimeric transcription factors. RUNX/CBFA plays important roles in hematopoiesis and may regulate the generation of hematopoietic stem cells from hematogenic endothelial cells. Deregulated expression of CBFA2/RUNX1 is associated with malignant diseases of the hematopoietic system. Human and mouse RUNX/CBFA share 95% amino acid sequence homology.

Long Name

Runt-related Transcription Factor 1

Alternate Names

AML1, CBFA2

Entrez Gene IDs

861 (Human); 12394 (Mouse); 50662 (Rat)

Gene Symbol

RUNX1

UniProt

Q01196

Additional RUNX1/CBFA2 Products

Product Documents for Human RUNX1/CBFA2 Alexa Fluor™ Plus 488‑conjugated Antibody

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Certificate of Analysis

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Product Specific Notices for Human RUNX1/CBFA2 Alexa Fluor™ Plus 488‑conjugated Antibody

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only