Human S1P4/EDG-6 Alexa Fluor® 750-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB10321S-100UG
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Human S1P4/EDG-6 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human S1P4/EDG‑6 transfectants but not the parental cell line in Flow Cytometry.
Source
Monoclonal Mouse IgG2B Clone # 1012512
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human S1P4/EDG‑6
Met1-Ile384
Accession # O95977
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
HEK293 Human Cell Line Transfected with Human S1P4/EDG-6 and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: S1P4/EDG-6

EDG-6 belongs to the G protein-coupled receptor 1 family. It is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. EDG-6 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P), a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. EDG-6 may be involved in cell migration processes that are specific for lymphocytes.

Long Name
Endothelial Differentiation Gene 5
Entrez Gene IDs
8698 (Human); 13611 (Mouse); 314649 (Rat)
Alternate Names
EDG6; EDG6S1P receptor Edg-6; Endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor6,endothelial differentiation, G protein coupled receptor 6; S1P receptor 4; S1P4; S1P4LPC1; S1PR4; SLP4; sphingosine 1-phosphate receptor 4; Sphingosine 1-phosphate receptor Edg-6; sphingosine-1-phosphate receptor 4

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