Human SF-1/NR5A1 MAb (Clone N1665)

R&D Systems | Catalog # PP-N1665-00

R&D Systems
Discontinued Product
PP-N1665-00 has been discontinued. An alternative/replacement product is available: PP-N1665-0C. View all SF-1/NR5A1 products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Western Blot, Immunoprecipitation

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # N1665
View all SF-1/NR5A1 Primary Antibodies »

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human SF-1/NR5A1 MAb (Clone N1665)

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Perfusion fixed paraffin-embedded sections of rat adrenal gland

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 2 reviews rated 5 using PP-N1665-00 in the following applications:

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: SF-1/NR5A1

Streroidogenic Factor 1 (SF-1, AD4BP, FTZ-F1; NR5A1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development, including the hypothalamic-pituitary-gonadal axis and sex determination.

Long Name

Steroidogenic Factor 1

Alternate Names

AD4BP, FTZF1, NR5A1, SF1

Entrez Gene IDs

2516 (Human)

Gene Symbol

NR5A1

Additional SF-1/NR5A1 Products

Product Documents for Human SF-1/NR5A1 MAb (Clone N1665)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human SF-1/NR5A1 MAb (Clone N1665)

For research use only

Citations for Human SF-1/NR5A1 MAb (Clone N1665)

Customer Reviews for Human SF-1/NR5A1 MAb (Clone N1665) (2)

5 out of 5
2 Customer Ratings
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

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  • Name: Anonymous
    Application: Immunohistochemistry-Paraffin
    Sample Tested: See PMID 23874227
    Species: Mouse
    Verified Customer | Posted 02/25/2015
  • Name: Anonymous
    Application: Immunofluorescence
    Sample Tested: See PMID 23874227
    Species: Mouse
    Verified Customer | Posted 02/25/2015

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Protocols

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FAQs

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