Human SLC7A5/LAT1 Alexa Fluor® 488-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB10390G-100UG
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Human SLC7A5/LAT1 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects Human SLC7A5/LAT1 in direct ELISAs.
Source
Monoclonal Mouse IgG Clone # BU53
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Plasma cell line 8226
Accession # Q01650
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 488

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Raji human Burkitt lymphoma cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: SLC7A5/LAT1

Human Large neutral amino acids transporter small subunit 1, also known as SLC7A5, CD98 Light Chain (CD98LC), 4F2 light chain and LAT1 belongs to the APC (Amino acid-Polyamine-organo Cation) superfamily and forms a heterodimer with SLC3A2 to function as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan.

Long Name
Solute Carrier Family 7 Member 5
Entrez Gene IDs
8140 (Human); 20539 (Mouse); 50719 (Rat)
Alternate Names
4F2 LC; 4F2LC; CD98; CD98lc; D16S469EL-type amino acid transporter 1; E16; Integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; LAT1; LAT1hLAT1; MPE16; MPE16CD98 light chain; SLC7A5; sodium-independent neutral amino acid transporter LAT1,4F2LC; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain; Solute carrier family 7 member 5; TA1; y+ system cationic amino acid transporter

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