SOCS (suppressor of cytokine signaling) proteins, also called CIS (cytokine-inducible SH2-domain containing) proteins, are a family of eight adaptor molecules active in signaling pathways that regulate innate and adaptive immune responses. All SOCS contain a single SH2 domain and a SOCS box, which recruits E3 ubiquitin ligase complexes, thus enhancing destruction of the molecules bound by SOCS proteins. SOCS proteins influence macrophage and dendritic cell activation and are essential for T cell development and differentiation.
Human SOCS-3 (NP_003946.3) VersaClone cDNA
R&D Systems | Catalog # RDC3553
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: SOCS-3
Long Name
Suppressor Of Cytokine Signaling 3
Alternate Names
ATOD4, CIS3, Cish3, SOCS3, SSI-3
Gene Symbol
SOCS3
UniProt
Additional SOCS-3 Products
Product Documents for Human SOCS-3 (NP_003946.3) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human SOCS-3 (NP_003946.3) VersaClone cDNA
For research use only
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