Human SOCS-3 (NP_003946.3) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human SOCS-3 (NP_003946.3) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: SOCS-3

SOCS (suppressor of cytokine signaling) proteins, also called CIS (cytokine-inducible SH2-domain containing) proteins, are a family of eight adaptor molecules active in signaling pathways that regulate innate and adaptive immune responses. All SOCS contain a single SH2 domain and a SOCS box, which recruits E3 ubiquitin ligase complexes, thus enhancing destruction of the molecules bound by SOCS proteins. SOCS proteins influence macrophage and dendritic cell activation and are essential for T cell development and differentiation.

Long Name
Suppressor Of Cytokine Signaling 3
Entrez Gene IDs
9021 (Human); 12702 (Mouse); 89829 (Rat)
Alternate Names
ATOD4; CIS3; CIS3CIS-3; Cish3; cytokine-induced SH2 protein 3; Cytokine-inducible SH2 protein 3; SOCS3; SOCS-3; SOCS-3STAT-induced STAT inhibitor 3; SSI-3; SSI-3ATOD4; SSI3MGC71791; suppressor of cytokine signaling 3


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