Detection of Somatostatin R2/SSTR2 in HEK293 Human Cell Line Transfected with Human Somatostatin R2/SSTR2 and eGFP by Flow Cytometry.
HEK293 human embryonic kidney cell line transfected with (A) human Somatostatin R2/SSTR2 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human Somatostatin R2/SSTR2 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # IC4224R). Quadrant markers were set based on isotype control antibody (Catalog # IC003R).View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Background: Somatostatin R2/SSTR2
Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.
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