Human Somatostatin R2/SSTR2 Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry View Larger

Detection of Somatostatin R2/SSTR2 in HEK293 Human Cell Line Transfected with Human Somatostatin R2/SSTR2 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human Somatostatin R2/SSTR2 or (B) irrelevant transfectants and eGFP were stained with Mouse Anti-Human Somatostatin R2/SSTR2 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # IC4224R). Quadrant markers were set based on isotype control antibody (Catalog # IC003R).View our protocol for Staining Membrane-associated Proteins.

Preparation and Storage

Background: Somatostatin R2/SSTR2

Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.

Product Datasheets

Related Research Areas

• Metabolic Peptide Hormones and Regulators
• Peptide Hormone G Protein-Coupled Receptors
• Somatostatin Receptors (SST)