Human Somatostatin R2/SSTR2 Antibody

Catalog # Availability Size / Price Qty
Somatostatin R2/SSTR2 in MDA-MB-231 Human Cell Line.
3 Images
Product Details
Citations (3)
Supplemental Products

Human Somatostatin R2/SSTR2 Antibody Summary

Species Reactivity
Detects human Somatostatin R2/SSTR2. Stains SSTR2 transfectants but not irrelevant transfectants.
Monoclonal Mouse IgG2A Clone # 402038
Protein A or G purified from hybridoma culture supernatant
NS0 mouse myeloma cell line transfected with Somatostatin R2/SSTR2
Accession # P30874
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

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Recommended Concentration
8-25 µg/mL
See below
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
8-25 µg/mL
See below
Intracellular Staining by Flow Cytometry
2.5 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunocytochemistry Somatostatin R2/SSTR2 antibody in MDA-MB-231 Human Cell Line by Immunocytochemistry (ICC). View Larger

Somatostatin R2/SSTR2 in MDA-MB-231 Human Cell Line. Somatostatin R2/SSTR2 was detected in immersion fixed MDA-MB-231 human breast cancer cell line using 10 µg/mL Human Somatostatin R2/SSTR2 Monoclonal Antibody (Catalog # MAB4224) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (brown; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Intracellular Staining by Flow Cytometry Detection of Somatostatin R2/SSTR2 antibody in MDA‑MB‑231 Human Cell Line antibody by Flow Cytometry. View Larger

Detection of Somatostatin R2/SSTR2 in MDA‑MB‑231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell line was stained with Human Somatostatin R2/SSTR2 Monoclonal Antibody (Catalog # MAB4224, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0101B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin.

Immunohistochemistry Somatostatin R2/SSTR2 antibody in Human Brain by Immunohistochemistry (IHC-P). View Larger

Somatostatin R2/SSTR2 in Human Brain. Somatostatin R2/ SSTR2 was detected in immersion fixed paraffin-embedded sections of human brain (cingulate cortex) using 3 µg/mL Human Somatostatin R2/SSTR2 Monoclonal Antibody (Catalog # MAB4224) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Somatostatin R2/SSTR2

Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.

Long Name
Somatostatin Receptor Type 2
Entrez Gene IDs
6752 (Human); 20606 (Mouse); 54305 (Rat)
Alternate Names
Smstr2; Somatostatin R2; somatostatin receptor 2; somatostatin receptor type 2; SomatostatinR2; SRIF-1; SS2R; SS-2-R; SS2-R; SST2; SSTR2

Product Datasheets

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Citations for Human Somatostatin R2/SSTR2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Combination of [177Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse Model
    Authors: M Simón, JT Jørgensen, HA Khare, C Christense, CH Nielsen, A Kjaer
    Pharmaceutics, 2022;14(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Primate cell fusion disentangles gene regulatory divergence in neurodevelopment
    Authors: RM Agoglia, D Sun, F Birey, SJ Yoon, Y Miura, K Sabatini, SP Pa?ca, HB Fraser
    Nature, 2021;0(0):.
    Species: Human
    Sample Types: Organoid
    Applications: ICC
  3. Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2.
    Authors: Parry JJ, Chen R, Andrews R
    Endocrinology, 2012;153(6):2747-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC


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Isotype Controls

Mouse IgG2A Isotype Control

Reconstitution Buffers

Secondary Antibodies

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