|Detection of Somatostatin R2/SSTR2 in HEK293 Human Cell Line Transfected with Somatostatin R2/SSTR2 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with Somatostatin R2/SSTR2 and eGFP was stained with Mouse Anti-Human Somatostatin R2/SSTR2 PE‑conjugated Monoclonal Antibody (Catalog # FAB4224P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.|
Somatostatin Receptor 2 (SSTR2) is one of five 7-transmembrane G-protein-coupled receptors for somatostatins 14 and 28. Human SSTR2 shares 84% aa identity with mouse SSTR2 within the extracellular domains. Isoform B (357 aa) has an alternate C-terminal cytoplasmic region that is 12 aa shorter than that of isoform A (369 aa, reported as 93 kDa). Both are expressed in brain, stomach, intestinal epithelia, pancreatic islets and kidney tubules. Isoform B is also expressed in parotid, thyroid and bronchial glands.
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