Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation.
Human STAT4 (NP_003142) VersaClone cDNA
R&D Systems | Catalog # RDC1453
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: STAT4
Long Name
Signal Transducer and Activator of Transcription 4
Alternate Names
signal transducer and activator of transcription 4, SLEB11
Gene Symbol
STAT4
UniProt
Additional STAT4 Products
Product Documents for Human STAT4 (NP_003142) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human STAT4 (NP_003142) VersaClone cDNA
For research use only
Related Research Areas
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