Transferrin receptors are transmembrane, homodimeric proteins that play a role in iron transport, uptake, and storage. TfR is an essential receptor, found on almost all cell types, regulated by intracellular iron concentration, and has a high affiinity for transferrin. Soluble TfR (sTfR) arises from the proteolysis of TfR into monomers that can be measured in plasma and serum. TfR2 has limited tissue distribution (hepatocytes and enterocytes), is regulated by the cell cycle, and binds transferrin poorly.
Human TfR2 (NP_003218) VersaClone cDNA
R&D Systems | Catalog # RDC1330
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TfR2
Long Name
Transferrin Receptor 2
Alternate Names
HFE3, TFRC2
Gene Symbol
TFR2
UniProt
Additional TfR2 Products
Product Documents for Human TfR2 (NP_003218) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human TfR2 (NP_003218) VersaClone cDNA
For research use only
Related Research Areas
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