Human TSPAN7 Alexa Fluor® 405-conjugated Antibody
Human TSPAN7 Alexa Fluor® 405-conjugated Antibody Summary
Accession # P41732
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
Tetraspanin-7 (aka TSPAN7, TALLA-1, TM4SF2 and CD231) is a 249 aminoacids (aa) multi-pass membrane protein. Tetraspanin proteins regulate morphology, signaling and trafficking processes by interaction and association with proteins in tetraspanin enriched microdomains (TEMs). It has been proposed that tetraspanins interact with integrins to affect cell migration, probably by modulation or compartmentalization of integrin signaling. TSPAN7 has been found to be upregulated in myeloma development and described as a prognostic marker of renal cell carcinoma. Mutations in TSPAN7 are also implicated in some forms of X-linked intellectual disability.
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