Human Vasohibin Isoform 1 Alexa Fluor® 350-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Vasohibin

Vasohibin is a secreted endothelium-derived negative feedback regulator of angiogenesis whose expression in endothelial cells is induced by proangiogenic growth factors such as VEGF and FGF-2. It is synthesized as a 365 amino acid residue protein that lacks a canonical signal peptide. As a result of proteolytic cleavage, multiple distinct molecular weight forms can be detected when Vasohibin is expressed on endothelial cells. Human and mouse Vasohibin share 93% amino acid sequence identity. Two splice variants of human Vasohibin have been reported.

Product Datasheets