Human Vasohibin Isoform 1 Antibody
Human Vasohibin Isoform 1 Antibody Summary
Accession # Q7L8A9
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Vasohibin is a secreted endothelium-derived negative feedback regulator of angiogenesis whose expression in endothelial cells is induced by proangiogenic growth factors such as VEGF and FGF-2. It is synthesized as a 365 amino acid residue protein that lacks a canonical signal peptide. As a result of proteolytic cleavage, multiple distinct molecular weight forms can be detected when Vasohibin is expressed on endothelial cells. Human and mouse Vasohibin share 93% amino acid sequence identity. Two splice variants of human Vasohibin have been reported.
Citation for Human Vasohibin Isoform 1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Alternative splicing of vasohibin-1 generates an inhibitor of endothelial cell proliferation, migration, and capillary tube formation.
Authors: Kern J, Bauer M, Rychli K, Wojta J, Ritsch A, Gastl G, Gunsilius E, Untergasser G
Arterioscler. Thromb. Vasc. Biol., 2008;28(3):478-84.
Sample Types: Cell Lysates
Applications: Western Blot
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