Human XPV Alexa Fluor® 750-conjugated Antibody

Catalog #: AF3417S Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3417S-100UG

Save 15% on Select RUO Reagents. See Details.

All XPV Antibodies

Product Details

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human XPV Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human XPV in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human XPV
Met1-Phe400
Accession # Q9Y253

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: XPV

Xeroderma pigmentosum variant (XPV) is a form of XP caused by mutation in the DNA polymerase eta (POLH) gene. DNA polymerase eta catalyzes translesion DNA synthesis past pyrimidine dimers, a mutation caused by exposure to ultraviolet (UV) light. XPV patients are sensitive to UV light and show an increased incidence of skin cancer.

Long Name

Xeroderma Pigmentosum Variant Type Protein

Entrez Gene IDs

5429 (Human); 80905 (Mouse); 316235 (Rat)

Alternate Names

DNA polymerase eta; DNA Polymerase, eta; EC 2.7.7.7; POLH; polymerase (DNA directed), eta; RAD30 homolog A; RAD30; RAD30A; RAD30AFLJ16395; Xeroderma pigmentosum variant type protein; XPV; XP-V; XPVFLJ21978