Chemical Name: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Biological ActivityAutophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro. Also inhibits TLR9.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells.
Lee HO, Mustafa A, Hudes GR, Kruger WD.
Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
Lamphier et al.
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VersaClone cDNA Plasmids
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