Catalog Number: 5648
Chemical Name: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
Biological Activity
Autophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro. Also inhibits TLR9.
Technical Data
  • M.Wt:
    433.95
  • Formula:
    C18H28ClN3O5S
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    747-36-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells.
    Lee et al.
    PLoS ONE, 2015;10:e0131464
  2. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.
    Lamphier et al.
    Mol.Pharmacol., 2014;85:429

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