Autophagy-related Compounds: Products

"Autophagy-related Compounds" has 58 results in Products.
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Dorsomorphin dihydrochloride 

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Thapsigargin 

Potent inhibitor of SERCA ATPase

Taxol 

Promotes assembly and inhibits disassembly of microtubules

Pepstatin A 

Selective and high affinity cathepsin D inhibitor

Everolimus 

mTOR inhibitor; Immunosuppressant

Bafilomycin A1 

H+-ATPase (vacuolar) inhibitor

Metformin hydrochloride 

Activator of LKB1/AMPK; antidiabetic agent

Dexamethasone 

Anti-inflammatory glucocorticoid

Rapamycin 

mTOR inhibitor; immunosuppressant

Tunicamycin 

Antibiotic; GlcNAc phosphotransferase inhibitor

A 769662 

Potent AMPK activator

Chloroquine diphosphate 

Antimalarial; inhibits apoptosis and autophagy

LY 294002 hydrochloride 

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Valproic acid, sodium salt 

Histone deacetylase inhibitor

Torin 1 

Potent and selective mTOR inhibitor

NF 449 

Highly selective P2X1 antagonist

Nocodazole 

Microtubule inhibitor

E 64d 

Cathepsin inhibitor; interferes with autolysosomal digestion

GF 109203X 

Protein kinase C inhibitor

Brefeldin A 

Disrupts protein translocation to Golgi

Pifithrin-α hydrobromide 

p53 inhibitor. Also aryl hydrocarbon receptor agonist

(±)-Bay K 8644 

CaV1.x activator

Nimodipine 

CaV1.x blocker

L-690,330 

Inositol monophosphatase inhibitor

Wortmannin 

Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1

A23187, free acid 

Calcium ionophore

Simvastatin 

HMG-CoA reductase inhibitor

Concanamycin A 

H+-ATPase (vacuolar) inhibitor

Temozolomide 

DNA-methylating antitumor agent

3-Methyladenine 

Class III PI 3-kinase inhibitor; also inhibits autophagy

Niclosamide 

STAT3 inhibitor; also inhibits mTORC1 signaling

SMER 28 

Positive regulator of autophagy

FK 866 hydrochloride 

Potent and non-competitive NAMPT inhibitor; induces apoptosis and autophagy

Hydroxychloroquine sulfate 

Autophagy inhibitor; also TLR9 inhibitor

NMS 873 

Potent and selective p97 ATPase (VCP) allosteric inhibitor

Nitrendipine 

CaV1.x blocker

Verapamil hydrochloride 

CaV1.x blocker

Vinblastine sulfate 

Disrupts microtubules

Rottlerin 

Reported PKCδ inhibitor

PI 103 hydrochloride 

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Amiodarone hydrochloride 

Broad spectrum ion channel blocker; antiarrhythmic

Carbamazepine 

Inhibitor of neuronal NaV channels; anticonvulsant

Torin 2 

Potent and selective mTOR inhibitor

DBeQ 

Selective and reversible p97 ATPase inhibitor

Xanthohumol 

p97 ATPase (VCP) inhibitor

MRT 67307 dihydrochloride 

Salt inducible kinase (SIK) inhibitor; also ULK1 and 2 inhibitor

ML 240 

ATP-competitive inhibitor of p97 ATPase

Temsirolimus 

mTOR inhibitor; antitumor

AS 1842856 

Potent and selective Foxo1 inhibitor; orally bioavailable

MRT 68921 dihydrochloride 

ULK inhibitor
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