ICAT/CTNNBIP1 Antibody (8F7O5)

Novus Biologicals | Catalog # NBP3-15319

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8F7O5 expressed in HEK293
View all ICAT Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-81 of human ICAT/CTNNBIP1 (Q9NSA3). MNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVNSQLSQLPPHSIDQGAEDVVMAFSRSETEDRRQ

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ICAT/CTNNBIP1 Antibody (8F7O5)

Western Blot: ICAT/CTNNBIP1 Antibody (8F7O5) [NBP3-15319]

Western Blot: ICAT/CTNNBIP1 Antibody (8F7O5) [NBP3-15319]

Western Blot: ICAT/CTNNBIP1 Antibody (8F7O5) [NBP3-15319] - Western blot analysis of extracts of TE-1 cells, using ICAT/CTNNBIP1 antibody (NBP3-15319) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Applications for ICAT/CTNNBIP1 Antibody (8F7O5)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ICAT

CTNNBIP1, or Beta-catenin-interacting protein 1, consists of a short 81 amino acid isoform that is approximately 9 kDa, and is involved in the negative regulation of the Wnt signaling pathway, and it also prevents CTNNB1 and TCF from interacting. Current research is being conducted on CTNNBIP1 and a number of diseases to determine the relationship between the two. Some of these disorders and diseases include: actinic cheilitis, nasopharyngitis, adenomatous polyposis coli, gastric cancer, cheilitis, esophagitis, esophageal squamous cell carcinoma, laryngitis, desmoid tumor, hepatocellular carcinoma, acute lymphoblastic leukemia, medulloblastoma, malignant glioma, duodenitis, wilms tumor, endometrial carcinoma, and polyposis. CTNNBIP1 is linked to the Wnt signaling pathway, where it interacts with JUP, CTNNB1, BEND5, CASP4, and CPVL.

Long Name

Beta-Catenin-Interacting Protein

Alternate Names

CTNNBIP1

Gene Symbol

CTNNBIP1

Additional ICAT Products

Product Documents for ICAT/CTNNBIP1 Antibody (8F7O5)

Certificate of Analysis

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Product Specific Notices for ICAT/CTNNBIP1 Antibody (8F7O5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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