Key Product Details

Species Reactivity

Mouse

Applications

Western Blot, Neutralization

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Goat IgG
View all IGFBP-2 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IGFBP‑2
Glu35-Gln305
Accession # CAA57270

Specificity

Detects mouse IGFBP‑2 in direct ELISAs and Western blots. In direct ELISAs, approximately 35% cross-reactivity with recombinant human (rh) IGFBP-2 is observed and less than 1% cross-reactivity with rhIGFBP-1, rhIGFBP-3, rhIGFBP-4, rhIGFBP-5, recombinant mouse (rm) IGFBP-3, rmIGFBP-4, rmIGFBP-5, and rmIGFBP-6 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for IGFBP-2 Antibody [PE]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IGFBP-2

IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is over expressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The over expression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

Long Name

Insulin-like Growth Factor Binding Protein 2

Alternate Names

IGFBP2

Gene Symbol

IGFBP2

Additional IGFBP-2 Products

Product Documents for IGFBP-2 Antibody [PE]

Certificate of Analysis

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Download SDS

Product Specific Notices for IGFBP-2 Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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