IKEPP Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-03308

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all IKEPP Primary Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human IKEPP (NP_079067.3). MEKAADLQDTASLTLKFKFNPKLGIDNPVLSLAEDHDPYDPWSLERPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQGLQEGDRILAVNNDVVEHEDYAVVVRRIRASSPRVLLTVLARHAHDVARAQLGEDAHLCPTLGPGVRPRLCHIVKDEGGFGFSVTHGNQGPFW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IKEPP Antibody - BSA Free

Western Blot: IKEPP AntibodyBSA Free [NBP3-03308]

Western Blot: IKEPP AntibodyBSA Free [NBP3-03308]

Western Blot: IKEPP Antibody [NBP3-03308] - Analysis of extracts of various cell lines, using IKEPP antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.

Applications for IKEPP Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IKEPP

IKEPP, also known as PDZD3, associates with GUCY2C to act as a regulatory protein and negatively modulates the heat-stable enterotoxin-mediated activation of GUCY2C. Specifically, IKEPP regulates the amount of cGMP produced following receptor stimulation. IKEPP has also been found to stimulate SLC9A3 activity in the presence of elevated calcium ions.

Alternate Names

FLJ22756, IKEPPPDZK2, intestinal and kidney enriched PDZ protein, Intestinal and kidney-enriched PDZ protein, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Na/Pi cotransporter C-terminal-associated protein 2, NaPi-Cap2, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, NHERF4, NHERF-4, PDZ domain containing 2, PDZ domain containing 3, PDZ domain-containing protein 2, PDZ domain-containing protein 3, Sodium-hydrogen exchanger regulatory factor 4

Gene Symbol

NHERF4

Additional IKEPP Products

Product Documents for IKEPP Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for IKEPP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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