IL-12 R beta 2 Antibody (305719) [Janelia Fluor® 549]

Name: IL-12 R beta 2 Antibody (305719) [Janelia Fluor® 549]
Brand: Novus Biologicals
SKU: FAB19592I
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # FAB19592I

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse

Applications

Direct ELISA

Label

Janelia Fluor 549

Antibody Source

Monoclonal Mouse IgG₁ Clone # 305719

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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IL-12 R beta 2
Cys28-Asn622
Accession # Q99665

Specificity

Detects human IL-12 R beta 2 in ELISA.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for IL-12 R beta 2 Antibody (305719) [Janelia Fluor® 549]

Application

Recommended Usage

Direct ELISA

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-12 R beta 2

IL12RB2 is encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq]

Long Name

Interleukin 12 Receptor beta 2

Alternate Names

IL-12Rb2, IL12R beta 2, IL12RB2

Additional IL-12 R beta 2 Products

Product Documents for IL-12 R beta 2 Antibody (305719) [Janelia Fluor® 549]

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Product Specific Notices for IL-12 R beta 2 Antibody (305719) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.