Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, CyTOF-ready

Label

Biotin

Antibody Source

Recombinant Monoclonal Rat IgG2B Clone # 888220
View all IL-15R alpha Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse IL-15 R alpha
Gly33-Lys205
Accession # Q60819

Specificity

Detects mouse IL-15 R alpha in direct ELISAs.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for IL-15R alpha Antibody (888220) [Biotin]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-15R alpha

IL15RA is a gene that codes for a protein that is a high-affinity receptor for interleukin-15, and can signal in both cis and trans to neighboring IL2RG-expressing cells, but the expression of different isoforms may interfere with this signal transduction, as isoforms 5-8 do not bind to IL15. The isoforms are all highly expressed in the brain, with isoform 1 being the longest with a 267 amino acid chain and a weight of approximately 28 kDa. Current studies are being done on several diseases and disorders relating to this gene including lymphoma, systemic lupus erythematosus, anemia, inflammatory bowel disease, leukemia, bronchiolitis, rheumatoid arthritis, hepatitis B, gingivitis, lung cancer and Alzheimer's disease. IL15Ra has also been shown to have interactions with SYK, IL2RB, TRAF2, and AXL in pathways such as the IL-15 signlaing, TCR signaling, and IgA production pathways.

Long Name

Interleukin 15 Receptor alpha

Alternate Names

CD215, IL-15 R alpha, IL-15Ra, IL15 R alpha, IL15RA

Gene Symbol

IL15RA

Additional IL-15R alpha Products

Product Documents for IL-15R alpha Antibody (888220) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for IL-15R alpha Antibody (888220) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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