Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)

Novus Biologicals | Catalog # NBP3-14633

Novus Biologicals
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Key Product Details

Sample Type & Volume Required Per Well

Serum, Plasma, Cell culture supernatant (50 ul)

Sensitivity

6.6 pg/ml

Assay Range

15.6-500 pg/ml
View all IL-17A/F Heterodimer ELISA Kits »

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Species

Human

Specificity

Recognizes both natural and recombinant human IL-17A/F Heterodimer

Description

Incubation: 3 hours 45 minutes

Precision

Intra-Assay Precision (Precision within an assay) CV% 7.5

Inter-Assay Precision (Precision between assays) CV% 7.2

Recovery for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)

Recovery

77 to 117%

Scientific Data Images for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)

ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633]

ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633]

ELISA: Human IL-17A/F Heterodimer ELISA Kit (Colorimetric) [NBP3-14633] - Example of Human IL-17A/F Heterodimer Standard Curve.

Kit Contents for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)

  • Biotinylated secondary antibody
  • Buffers
  • Controls (where applicable)
  • Detailed procedure.
  • Pre-coated strip plates
  • Standards
  • Stop reagents
  • Streptavidin-HRP
  • TMB

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IL-17A/F Heterodimer

IL-17A/F is a secreted disulfide-linked heterodimer of the cytokines IL-17A and IL-17F. IL-17A/F and the IL-17A and IL-17F homodimers are produced by IL-23 activated Th17 cells. The widely expressed receptors IL-17 RA and IL-17 RC form a heterodimer for the binding of IL-17A and IL-17F, as well as the heterodimeric IL-17A/F. IL-17A/F is a biologically active protein that induces chemokine production and airway neutrophilia with intermediate potency between IL-17A (most potent) and IL-17F (least potent). It is upregulated in immune cells during inflammatory arthritis and contributes to disease severity.

Long Name

Interleukin 17 A/F

Alternate Names

CTLA8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, Cytotoxic T-Lymphocyte-Associated Protein 8, IL17, IL-17, IL-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A, interleukin-17A

Gene Symbol

IL17A

Additional IL-17A/F Heterodimer Products

Product Documents for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)

Certificate of Analysis

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Product Specific Notices for Human IL-17A/F Heterodimer ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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