Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

E. coli-derived recombinant human IL-17B (R&D Systems, Catalog # 1248-IB)
Gln21-Phe180
Accession # Q9UHF5

Specificity

Detects human and mouse IL-17B in direct ELISAs and Western blots. In these formats, less than 5% cross‑reactivity with recombinant human (rh) IL-17, rhIL-17C, rhIL-17E, and rhIL-17F is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for IL-17B Antibody [DyLight 350]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-17B

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are IL-17B, IL-17C, and IL-17E. Like IL-17, IL-17B, C, and E are able to induce proinflammatory responses but don't bind to the IL-17 receptor suggesting additional IL-17R related receptors might exist. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in kidney and liver and at moderate level in small intestine, colon, and brain.

Long Name

Interleukin 17B

Alternate Names

IL17B

Gene Symbol

IL17B

Additional IL-17B Products

Product Documents for IL-17B Antibody [DyLight 350]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IL-17B Antibody [DyLight 350]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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FAQs

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Associated Pathways

IL-17 Family Signaling Pathways IL-17 Family Signaling Pathway Thumbnail