IL-17RD, also known as SEF, is a 120 kDa type I transmembrane glycoprotein that is found in both the cytoplasm and plasma membrane. The membrane-bound long form of human IL-17RD is synthesized as a 739 amino acid (aa) precursor protein with a 27 aa signal peptide, a 272 aa extracellular domain, a 20 aa transmembrane segment and a 420 aa cytoplastic domain. Natural IL-17RD has been shown to form homomultimeric complexes.
IL-17RD/SEF Antibody (309539) [Biotin]
Novus Biologicals | Catalog # FAB2275B
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Biotin
Antibody Source
Monoclonal Mouse IgG2B Clone # 309539
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL‑17 RD/SEF
Ala27-Arg299
Accession # AAM77571
Ala27-Arg299
Accession # AAM77571
Specificity
Detects human IL‑17 RD/SEF in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse IL-17 RD, recombinant human (rh) IL-17 RC, or rhIL-17B R is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for IL-17RD/SEF Antibody (309539) [Biotin]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IL-17RD/SEF
Long Name
Interleukin 17 Receptor D, Transcript Variant 3
Alternate Names
IL-17 RD, IL17RD, IL17RLM, SEF
Gene Symbol
IL17RD
Additional IL-17RD/SEF Products
Product Documents for IL-17RD/SEF Antibody (309539) [Biotin]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for IL-17RD/SEF Antibody (309539) [Biotin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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