IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.
Non-human Primate IL-23 ELISA Kit
Novus Biologicals | Catalog # NBP3-11730
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Key Product Details
Sample Type & Volume Required Per Well
Serum, plasma, cell culture supernatants (100 uL)
Sensitivity
5 pg/mL
Assay Range
10 - 3160 pg/mL
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Product Specifications
Kit Type
ELISA Kit
Species
Non-human Primate
Precision
Intra-Assay Precision (Precision within an assay) %CV 5.8
Inter-Assay Precision (Precision between assays) %CV 15.6
Recovery for Non-human Primate IL-23 ELISA Kit
Recovery
90 - 107%
Scientific Data Images for Non-human Primate IL-23 ELISA Kit
ELISA: Non-human Primate IL-23 ELISA Kit [NBP3-11730]
ELISA: Non-human Primate IL-23 ELISA kit [NBP3-11730] - Representative standard curveKit Contents for Non-human Primate IL-23 ELISA Kit
- Biotinylated detection mAb (MT155)
- Buffers for washing and dilution and standard reconstitution
- Pre-coated ELISA strip plates (mAbs MT86/221)
- Recombinant human IL-23 ELISA standard
- Streptavidin-HRP
- Substrate (TMB)
Preparation and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Storage of components varies. See protocol for specific instructions.
Background: IL-23
Long Name
Interleukin 23
Alternate Names
IL-23 p19/IL-12 p40, IL-23p19/IL-12p40, IL23, SGRF
Gene Symbol
IL23A
Additional IL-23 Products
Product Documents for Non-human Primate IL-23 ELISA Kit
Product Specific Notices for Non-human Primate IL-23 ELISA Kit
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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