454 results for "IL-23" in Products
IL-23 Products
IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.
| Reactivity: | Human |
| Applications: |
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Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies
| Reactivity: | Mouse |
| Applications: |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, B/N |
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
| Reactivity: | Human |
| Applications: |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Reactivity: | Mouse |
| Applications: |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #727753 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG2B Monoclonal Clone #1193B |
| Applications: | WB, B/N |
Analyzed by SEC-MALS.
| Reactivity: | Mouse |
| Source: | HEK293 |
| Accession #: | P43432.1 (p40) & Q9EQ14.1 (p19) |
| Applications: | Bioactivity |
| Reactivity: | Rat |
| Source: | Sf 21 (baculovirus) |
| Accession #: | NP_072133 (p40) & NP_569094 (p19) |
| Applications: | Bioactivity |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #320234 |
| Applications: | WB, ELISA(Cap) |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #320229 |
| Applications: | WB |
Analyzed by SEC-MALS
| Reactivity: | Human |
| Source: | CHO |
| Applications: | Bioactivity |
| Reactivity: | Human, Feline |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Canine |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | P29460.1 & AAG37232.1 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Applications: |
| Reactivity: | Cynomolgus Monkey |
| Applications: |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #JE38-99 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Rat |
| Sensitivity: | 9.38 pg/mL |
| Assay Range: | 15.63 - 1000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 23.44 pg/mL |
| Assay Range: | 39.06 - 2500 pg/mL |
| Applications: | ELISA |