Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
IL-29/IFN-lambda 1 Antibody (B-S29) - Azide and BSA Free
Novus Biologicals | Catalog # NBP3-18106
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2b Kappa Clone # B-S29
Format
Azide and BSA Free
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Product Specifications
Immunogen
Recombinant human IL-29/IFN-lambda 1. Hybridoma: Myeloma X63/AG.8653 x Balb/c node cells
Specificity
Recognizes both natural and recombinant human IL-29/IFN-lambda 1
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2b Kappa
Description
Novus Biologicals Mouse IL-29/IFN-lambda 1 Antibody (B-S29) - Azide and BSA Free (NBP3-18106) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Applications for IL-29/IFN-lambda 1 Antibody (B-S29) - Azide and BSA Free
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS. Sterile-filtered through 0.22 um.
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -70C long term. Avoid freeze-thaw cycles.
Background: IL-29/IFN-lambda 1
Long Name
Interleukin 29
Alternate Names
IFN-lambda 1, IL29
Gene Symbol
IFNL1
Additional IL-29/IFN-lambda 1 Products
Product Documents for IL-29/IFN-lambda 1 Antibody (B-S29) - Azide and BSA Free
Product Specific Notices for IL-29/IFN-lambda 1 Antibody (B-S29) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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